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Stefani and Rigacci 2013 )

Furthermore, no studies to date have reported pharmacokinetic parameters (e.g., absorption, bioavailability, tissue distribution), nor have they conducted long-term toxicity assessments or evaluated reproductive outcomes in vivo

We reminded readers to visit the CMS resource library website at and the ONC website at for resources on the content and appropriate use of the SAFER Guides (88 FR 59262)